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Submit ReviewAdenosine is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes.
Adenosine is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
分子量 | 267.24 |
公式 | C10H13N5O4 |
储存 | Store at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 58-61-7 |
PubChem ID | 60961 |
InChI Key | OIRDTQYFTABQOQ-KQYNXXCUSA-N |
Smiles | O[C@@H]1[C@@H](CO)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 2.67 | 10 | |
DMSO | 20.04 | 75 |
以下数据基于产品分子量 267.24。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.75 mM | 4.99 mL | 24.95 mL | 49.89 mL |
3.75 mM | 1 mL | 4.99 mL | 9.98 mL |
7.5 mM | 0.5 mL | 2.49 mL | 4.99 mL |
37.5 mM | 0.1 mL | 0.5 mL | 1 mL |
参考文献是支持产品生物活性的出版物。
Jacobson and Gao (2006) Adenosine receptors as therapeutic targets. Nat.Rev.Drug Discov. 5 247 PMID: 16518376
If you know of a relevant reference for Adenosine, please let us know.
关键词: Adenosine, Adenosine supplier, Endogenous, adenosines, receptor, agonists, Non-Selective, Receptors, Non-selective, Adenosine, 3624, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Adenosine 的部分引用包括:
Bumpus and Johnson (2011) 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated J Neurosci 339 886 PMID: 21896918
Giovanni et al (2021) Specific and behaviorally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK. Neuron 109 2256-2274.e9 PMID: 34139149
Bruce R et al (2022) Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses. Cell Rep 39 110727 PMID: 35443187
Hao et al (2019) A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine. Neuron 102 745-761.e8 PMID: 30922875
Thomas C et al (2019) Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell 179 498-513.e22 PMID: 31585084
Hamby et al (2012) Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. PLoS One 32 14489 PMID: 23077035
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