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AG 045572

Cat. No. 2730 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2730 has been discontinued.

View all Gonadotropin-Releasing Hormone Receptors products.
说明： Selective GnRH receptor antagonist
化学名： 5-[5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl-methyl]-N-(2,4,6-trimethoxyphenyl)-2-furancarboxamide
纯度： ≥97% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for AG 045572

AG 045572 is a selective gonadotropin-releasing hormone (GnRH) receptor antagonist (Ki values are 2.2, 3.8 and 6.0 nM for mouse, rat and human receptors respectively). Suppresses testosterone and luteinising hormone (LH) levels in vivo.

技术数据 for AG 045572

分子量 491.62
公式 C30H37NO5
储存 Store at RT
纯度 ≥97% (HPLC)
CAS Number 263847-55-8
PubChem ID 9957278
InChI Key IPEMCIBPDYCJLO-UHFFFAOYSA-N
Smiles CC(CCC(C)2C)(C)C1=C2C=C(C)C(CC3=CC=C(C(NC4=C(OC)C=C(OC)C=C4OC)=O)O3)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for AG 045572

参考文献是支持产品生物活性的出版物。

Iatsimirskaia et al (2002) Effect of testost. suppression on the pharmacokinetics of a potent GnRH receptor antagonist. Pharm.Res. 19 202 PMID: 11883648

Anderes et al (2003) Biological characterization of a novel, orally active small molecule gonadotropin-releasing hormone (GnRH) antagonist using castrated and intact rats. J.Pharmacol.Exp.Ther. 305 688 PMID: 12606616

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关键词: AG 045572, AG 045572 supplier, Selective, GnRH, receptor, antagonists, Receptors, Gonadotrophin-Releasing, Hormone, AG045572, gonadotropin, 2730, Tocris Bioscience

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