主页 / 药理学 / GPCRs / 7-TM Receptors / Prostanoid Receptors / Alprostadil

Alprostadil

Cat. No. 1620 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Prostaglandin. Vasodilator and antiplatelet agent in vivo
别名： PGE1,Prostaglandin E1
化学名： (11α,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oic acid
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Alprostadil

Alprostadil is a prostaglandin with some selectivity for EP3 and EP4 receptors (Ki values are 1.1, 2.1, 36, 10 and 33 nM for mouse EP3, EP4, EP1, EP2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo.

技术数据 for Alprostadil

分子量 354.49
公式 C20H34O5
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 745-65-3
PubChem ID 5280723
InChI Key GMVPRGQOIOIIMI-DWKJAMRDSA-N
Smiles CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Alprostadil

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 17.72 50

制备储备液 for Alprostadil

以下数据基于产品分子量 354.49。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 5.64 mL 28.21 mL 56.42 mL
2.5 mM 1.13 mL 5.64 mL 11.28 mL
5 mM 0.56 mL 2.82 mL 5.64 mL
25 mM 0.11 mL 0.56 mL 1.13 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

产品说明书 for Alprostadil

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Alprostadil

参考文献是支持产品生物活性的出版物。

Kiriyama et al (1997) Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 122 217 PMID: 9313928

Kirtland (1988) Prostaglandin E1: a review. Prostaglandins Leukot.Essent.Fatty Acids 32 165 PMID: 2901111

Whittle et al (1985) Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets. Adv.Exp.Med.Biol. 192 109 PMID: 2871707

If you know of a relevant reference for Alprostadil, please let us know.

按标靶查看相关产品

关键词: Alprostadil, Alprostadil supplier, Prostaglandin, Vasodilator, anti-platelet, agent, vivo, Receptors, TP, EP1, EP2, EP3, EP4, Prostanoid, prostaglandins, prostacyclins, eicosanoids, PGE1, E1, 1620, Tocris Bioscience

1 篇 Alprostadil 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Alprostadil 的部分引用包括：

Bisikirska et al (2016) Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression. Cancer Res 76 664 PMID: 26589882

您是否知道使用了 Tocris Alprostadil 的优秀论文？ 请告知我们.

Alprostadil 的评论

目前没有该产品的评论。 Be the first to review Alprostadil and earn rewards!

Have you used Alprostadil?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review