AM 92016 hydrochloride

Name: AM 92016 hydrochloride
Brand: Tocris Bioscience
SKU: 0876
Rating: 5 (1 reviews)

Cat. No. 0876 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0876 has been discontinued.

View all Voltage-gated Potassium (K<sub>V</sub>) Channels products.

说明： K_V channel blocker

化学名： 1-(4-Methanesulfonamidophenoxy)-3-(N-methyl-3,4-dichlorophenylethylamino)-2-propanol hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for AM 92016 hydrochloride

A specific blocker of the time dependent delayed rectifier potassium current, devoid of any β-adrenoceptor blocking activity. Exhibits proarrhythmic and prohypertensive activity in vivo.

技术数据 for AM 92016 hydrochloride

分子量	483.84
公式	C₁₉H₂₄Cl₂N₂O₄S.HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	133229-11-5
PubChem ID	45073415
InChI Key	TXOARFPCQOBODS-UHFFFAOYSA-N
Smiles	Cl.CN(CCC1=CC(Cl)=C(Cl)C=C1)CC(O)COC1=CC=C(NS(C)(=O)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for AM 92016 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for AM 92016 hydrochloride

参考文献是支持产品生物活性的出版物。

Conners et al (1992) Actions and mechanisms of action of novel analogues of sot. on guinea-pig and rabbit ventricular cells. Br.J.Pharmacol. 106 958 PMID: 1393293

Hagerty et al (1996) The in vivo cardiovascular effects of a putative class III anti-arrhythmic drug, AM 92016. J.Pharm.Pharmacol. 48 417 PMID: 8794994

Lei and Brown (1998) Inhibition by compound II, a sot. analogue, of delayed rectifier current (i_K) in rabbit sino-atrial node cells. Naunyn Schmiedebergs Arch.Pharmacol. 357 260 PMID: 9550297

Palen et al (2005) Role of SHP-1, Kv1.2 and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells. Cardiovasc.Res. 68 268 PMID: 15967421

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篇 AM 92016 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 AM 92016 hydrochloride 的引用文献。