Ambuic Acid

Discontinued Product

6547 has been discontinued.

View all Antibiotics products.
说明: Quorum sensing inhibitor; antibacterial
化学名: (2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid
纯度: ≥95% (HPLC)
说明书
引用文献
评论

生物活性 for Ambuic Acid

Quorum sensing inhibitor. Inhibits auto-inducing peptide (AIP) signal biosynthesis in MRSA (IC50 = 2.5 μM). Reduces MRSA-induced abcess formation in rats. Exhibits activity against pathogenic Gram-positive bacteria but not commensal bacteria.

技术数据 for Ambuic Acid

分子量 350.41
公式 C19H26O6
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 340774-69-8
PubChem ID 11152290
InChI Key UDSQZJMGPSRCEM-HDKVZZTHSA-N
Smiles CCCCC/C=C/C1=C([C@H]([C@H]2O[C@]2(C1=O)C/C=C(C(O)=O)\C)O)CO

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Ambuic Acid

参考文献是支持产品生物活性的出版物。

Todd et al (2017) Signal biosynthesis inhibition with ambuic acid as a strategy to target antibiotic-resistant infections. Antimicrob.Agents Chemother. 61 e00263-17 PMID: 28607020

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关键词: Ambuic Acid, Ambuic Acid supplier, quorum, sensing, inhibitors, inhibits, antibacterial, auto-inducing, peptide, AIP, signal, biosynthesis, MRSA, methicillin, meticillin, resistant, Staphylococcus, aureus, Antibiotics, 6547, Tocris Bioscience

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