Antibiotics

Antibiotics are compounds used to treat or prevent bacterial infections by killing or inhibiting growth of bacteria. They are also used in cell culture to prevent contamination, particularly by Mycoplasma species. Antibiotics may be chemically synthesized or isolated from natural sources, such as fungi.

Products
Cat. No. Product Name / Activity
1234 A23187, free acid
Calcium ionophore
1515 17-AAG
Selective Hsp90 inhibitor
1229 Actinomycin D
Inhibits RNA polymerase
1290 Anisomycin
Protein synthesis inhibitor
5736 Aphidicolin
Antibiotic; inhibits DNA polymerase α, δ and ε
3771 Azithromycin
Antibiotic; inhibits 50S ribosomal subunit formation and elongation at transpeptidation
1334 Bafilomycin A1
H+-ATPase (vacuolar) inhibitor
5502 Blasticidin S HCl
Antibiotic; selection reagent for bis, bsr and BSD transformed cells
2656 Concanamycin A
H+-ATPase (vacuolar) inhibitor
0970 Cycloheximide
Inhibitor of protein synthesis
3917 Daptomycin
Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria
1467 Daunorubicin hydrochloride
RNA synthesis inhibitor; anthracycline
2252 Doxorubicin hydrochloride
Antitumor antibiotic agent. Inhibits DNA topoisomerase II
4090 Doxycycline hyclate
Broad-spectrum antibiotic and MMP inhibitor
6250 Filipin III
Polyene antibiotic; inhibits formation of pathological isoform of prion protein
3631 FK 506
Potent calcineurin inhibitor; immunosuppressant
4131 G418 disulfate salt
Aminoglycoside antibiotic; used in cell culture
1368 Geldanamycin
Selective Hsp90 inhibitor
6442 Gentamicin sulfate
Aminoglycoside antibiotic
1629 Herbimycin A
Src family kinase inhibitor. Also Hsp90 inhibitor
4137 Hygromycin B
Aminoglycoside antibiotic; active against prokaryotic and eukaryotic cells
2611 IMD 0354
Potent antibacterial against multidrug-resistant gram-positive bacteria; IKKβ inhibitor
1704 Ionomycin calcium salt
Calcium ionophore
2092 Ionomycin free acid
Calcium ionophore
3765 Linezolid
Antibiotic; inhibits protein synthesis in gram-positive bacteria
6856 α-Mangostin
Inhibits MRSA and VRE; anticarcinogenic and neuroprotective
3268 Minocycline hydrochloride
Antibiotic. Displays neuroprotective effects
1489 Mithramycin A
Anticancer antibiotic
3258 Mitomycin C
Antibiotic and antitumor agent
4110 Oligomycin A
Antibiotic; exhibits anti-tumor activity
4089 Puromycin dihydrochloride
Aminonucleoside antibiotic
1589 Radicicol
Antifungal antibiotic
1292 Rapamycin
mTOR inhibitor; immunosuppressant
1592 SCH 79797 dihydrochloride
Broad spectrum antibiotic; inhibits DHFR and disrupts bacterial cell membrane; also potent and selective PAR1 antagonist
7449 Se-NADA
Photosensitizer, brings about bacterial cell death on exposure to visible light; also orange fluorescent benzoselenadiazole D-amino acids (FDAA) for imaging bacteria
1621 Streptozocin
Antibiotic and antitumor agent
3607 SU 3327
Antibiotic; Selective JNK inhibitor
5390 Tobramycin
Aminoglycoside antibiotic
5270 Toyocamycin
Adenosine analog; antifungal antibiotic
3863 Trovafloxacin mesylate
Antibiotic; inhibits bacterial DNA synthesis
3516 Tunicamycin
Antibiotic; inhibits protein glycosylation
3373 Valinomycin
Selective K+ ionophore
5506 Vancomycin HCl
Antibiotic
3787 Viomycin
Antibiotic; inhibits bacterial DNA synthesis