Apelin-36 (rat, mouse)

Name: Apelin-36 (rat, mouse)
Brand: Tocris Bioscience
SKU: 2427

Cat. No. 2427 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2427 has been discontinued.

View all Apelin Receptors products.

说明： Endogenous apelin agonist

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Apelin-36 (rat, mouse)

Apelin-36 (rat, mouse) is an endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC₅₀ = 5.4 nM) and potently inhibits cAMP production in vitro (EC₅₀ = 0.52 nM). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

技术数据 for Apelin-36 (rat, mouse)

分子量	4200.93
公式	C₁₈₅H₃₀₄N₆₈O₄₃S
序列	LVKPRTSRTGPGAWQGGRRKFRRQRPRLSHKGPMPF
储存	Desiccate at -20°C
CAS Number	230299-95-3
PubChem ID	90488763
InChI Key	NRXGOOSANFUBIE-ZINMNJNTSA-N
Smiles	[H]N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Apelin-36 (rat, mouse)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Apelin-36 (rat, mouse)

参考文献是支持产品生物活性的出版物。

Zou et al (2000) Apelin peptides block the entry of human immunodeficiency virus (HIV). FEBS Lett. 473 15 PMID: 10802050

Kawamata et al (2001) Molecular properties of apelin: tissue distribution and receptor binding. Biochim.Biophys.Acta 1538 162 PMID: 11336787

Tatemoto et al (1998) Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem.Biophys.Res.Comm. 251 471

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关键词: Apelin-36 (rat, mouse), Apelin-36 (rat, mouse) supplier, Endogenous, APJ, receptors, agonists, Apelin, adipokines, Receptors, 2427, Tocris Bioscience

篇 Apelin-36 (rat, mouse) 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Apelin-36 (rat, mouse) 的引用文献。