Arachidonyl serotonin

Name: Arachidonyl serotonin
Brand: Tocris Bioscience
SKU: 2836

Cat. No. 2836 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2836 has been discontinued.

View all Other Cannabinoids products.

说明： Dual FAAH inhibitor/TRPV1 antagonist

别名： AA-5-HT

化学名： N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Arachidonyl serotonin

Arachidonyl serotonin is a dual fatty acid amide hydrolase (FAAH) inhibitor/TRPV1 antagonist (IC₅₀ values are 5.6 μM and 37 - 40 nM for FAAH and TRPV1 respectively). Inactive at cPLA₂, CB₁ or 5-HT receptors. Displays strong analgesic activity against both acute and chronic peripheral pain.

技术数据 for Arachidonyl serotonin

分子量	462.67
公式	C₃₀H₄₂N₂O₂
储存	Store at -20°C
CAS Number	187947-37-1
PubChem ID	10027372
InChI Key	QJDNHGXNNRLIGA-DOFZRALJSA-N
Smiles	O=C(NCCC1=CNC2=C1C=C(O)C=C2)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Arachidonyl serotonin

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Arachidonyl serotonin

参考文献是支持产品生物活性的出版物。

Di Marzo et al (2004) The endocannabinoid system and its therapeutic exploitation. Nat.Rev.Drug Discov. 3 771 PMID: 15340387

Maione et al (2007) Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br.J.Pharmacol. 150 766 PMID: 17279090

Bisogno et al (1998) Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochem.Biophys.Res.Comms. 248 515

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