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ARN 14686

Cat. No. 5862 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5862 has been discontinued.

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说明： Potent N-acylethanolamine acid amidase inhibitor; NAAA activity-based protein profiling (ABPP) probe
化学名： (S)-Undec-10-yn-1-yl (2-oxoazetidin-3-yl)carbamate
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for ARN 14686

ARN 14686 is a NAAA (N-acylethanolamine acid amidase) activity-based protein profiling (ABPP) probe. Can be used to detect NAAA in cell lysates or intact cells. Covalently binds the N-terminal cysteine of catalytically active NAAA. Detects catalytically active NAAA in inflamed rat paw in CFA model of inflammation. Potent NAAA inhibitor (IC50 = 6 nM).

技术数据 for ARN 14686

分子量 280.36
公式 C15H24N2O3
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1628345-10-7
PubChem ID 118915444
InChI Key XEXRAYPXQNELAS-ZDUSSCGKSA-N
Smiles O=C(OCCCCCCCCCC#C)N[C@H]1CNC1=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for ARN 14686

参考文献是支持产品生物活性的出版物。

Romeo et al (2015) Activity-based probe for N-acylethanolamine acid amidase. ACS Chem.Biol. 10 2057 PMID: 26102511

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关键词: ARN 14686, ARN 14686 supplier, ARN14686, NAAA, N-acylethanolamine, acid, amidase, activity-based, protein, profiling, ABPP, probes, inhibits, inhibitors, Other, Hydrolases, Biochemicals, and, Molecular, Biology, 5862, Tocris Bioscience

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