Modulators |
Cat. No. |
Product Name / Activity |
8063 |
CHDI 113 |
| Potent HTT pre-RNA splicing modulator |
Ligands |
Cat. No. |
Product Name / Activity |
8042 |
Alkyne-cRGD |
| Integrin ligand for degrader development and targeted delivery, with alkyne click handle for conjugation |
Building Blocks |
Cat. No. |
Product Name / Activity |
7921 |
DBCO-NHS |
| Amine reactive and azide reactive building block |
7900 |
SCOTfluor 510 Fmoc-Dapa-OH New |
| Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes |
Controls |
Cat. No. |
Product Name / Activity |
7789 |
IA |
| SHAPE-JuMP monoaduct control for TBIA (Cat.No. 7788) |
Other |
Cat. No. |
Product Name / Activity |
6602 |
1M7 |
| Reagent for RNA SHAPE-MaP chemistry |
7376 |
2A3 |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable |
5113 |
AbK |
| Photo-crosslinking probe; unnatural amino acid |
7936 |
Ac-Cys-NHMe |
| Building block for the lysine acylation using conjugating enzymes (LACE) technique |
7932 |
Ac4GalN6yne |
| Alkyne containing monosaccharide building block; used in BOCTAG |
8035 |
Ac4GalNAlk |
| Metabolic chemical reporter for studying glycosylation and glycoproteins |
7479 |
Ac4ManNAz |
| Azide-containing monosaccharide building block; used as glycoprotein, glycolipid and glycoRNA probe |
7553 |
Ac4ManNDAz |
| Photo-crosslinking probe for studying glycoproteins and glycolipids |
3525 |
ACSF (Artificial Cerebrospinal Fluid) |
| Artificial cerebrospinal fluid (ACSF) for electrophysiology; sterile and microfiltered |
6930 |
Amphotericin B |
| Forms monovalent ion channels in lipid bilyers; antifungal |
5962 |
3-AP |
| Iron chelator; ribonucleotide reductase inhibitor |
6834 |
Auxin |
| Chemical dimerizer used in auxin-inducible degron (AID) system; phytohormone |
6584 |
L-Azidohomoalanine hydrochloride |
| Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins |
6585 |
L-Azidonorleucine hydrochloride |
| Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins |
2786 |
BAPTA |
| Selective calcium chelator |
2787 |
BAPTA AM |
| Cell-permeable Ca2+ chelator |
3349 |
Biocytin |
| Versatile marker for neuroanatomical investigations |
6571 |
Biotin-11-dUTP |
| Biotin-labeled dUTP |
6572 |
Biotin-LC-NAD+ |
| Biotinylated analog of β-NAD+; commonly used reagent in LSD1 and PARP1 assays |
6573 |
Biotin-NAD+ |
| Biotinylated-NAD+; substrate for ADP-ribosylation |
7524 |
Biotin-PEG3-Azide |
| Biotin with PEG linker and reactive click handle |
5502 |
Blasticidin S HCl |
| Antibiotic; selection reagent for bis, bsr and BSD transformed cells |
5015 |
5-BrdU |
| Synthetic thymidine analog; used for cell proliferation assays |
8059 |
BTD S-sulfenic acid probe New |
| Chemoproteomic reagent for targeting S-sulfenic acids on SulfenQ platform, alkyne handle for click chemistry |
5476 |
Cell Activation Cocktail 500X |
| Cell activation cocktail |
7368 |
Cell Counting Kit-8 |
| Cell viability and proliferation assay test solution |
8108 |
CEP |
| Chemoproteomic reagent, clickable electrophilic purine for RNA binding profiling in live cells |
7769 |
Chem-CLIP control probe |
| Control probe for Chem-CLIP experiments |
7945 |
Cholesterol |
| Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity |
6798 |
Click N-Acetylmuramic acid - alkyne |
| Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes |
7506 |
Click N-Acetylmuramic acid - azide |
| Bacterial peptidoglycan derivative; suitable for 'click'-conjugation to fluorescent dyes |
3180 |
α-Cyclodextrin |
| Cyclic complexing agent |
3181 |
β-Cyclodextrin |
| Cyclic complexing agent |
7480 |
DBCO PEG4 Biotin |
| Biotinylation reagent for labeling azide-containing biomolecules via Cu(I)-free click chemistry |
6175 |
DBHDA |
| Reagent for synthetic biology; converts cysteine to dehydroalanine |
7176 |
DC-Cholesterol hydrochloride |
| Liposomal transfection reagent |
5764 |
Deferoxamine mesylate |
| Iron chelator; also hypoxia mimetic and neuroprotectant |
7768 |
Disulfide biotin azide |
| Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry |
3154 |
DL-Dithiothreitol |
| Maintains SH groups in the reduced state |
7946 |
DLin-MC3-DMA |
| Ionizable cationic lipid |
7944 |
DMG-PEG 2000 |
| PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs) |
3176 |
DMSO, sterile filtered |
| DMSO, sterile filtered, wide ranging applications in cell culture, cryopreservation and organic chemistry. Solvent for polar and nonpolar compounds |
7726 |
DMSO, Cell Cryopreserve Grade |
| Intracellular cryoprotective agent |
7175 |
DOPE |
| Liposome/lipoplex transfection enhancer |
7179 |
DOTAP |
| Cationic agent for liposome and LNP formation |
7943 |
DSPC |
| Neutral phospholipid; component of lipid nanoparticles (LNPs) |
7947 |
DSPE-PEG 2000 Maleimide |
| PEGylated DSPE with a maleimide reactive group |
6785 |
E 7820 |
| Molecular glue; also α2 integrin inhibitor |
2807 |
EGTA |
| Calcium chelating agent |
7206 |
5-Ethynyluridine |
| Uridine analog, used for labeling RNA synthesis |
6253 |
F 127 (20% solution in DMSO) |
| Nonionic detergent |
8011 |
FAI |
| Reagent for RNA SHAPE-MaP experiments in live cells |
6574 |
Fluorescein-NAD+ |
| Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays |
7780 |
β-GalNAc-PEG4-Azide |
| Functionalized Asialoglycoprotein receptor ligand, for targeting conjugates to hepatocytes |
4991 |
HaXS8 |
| Chemical dimerizer |
7046 |
1,6-Hexanediol |
| Tool for probing liquid-liquid phase separation |
0708 |
2-Hydroxypropyl-β-cyclodextrin |
| Solubilization agent |
7015 |
IA-Alkyne |
| Broad spectrum cysteine reactive probe |
4299 |
iCRT 14 |
| Transfection enhancer; also inhibits β-catenin-responsive transcription |
6782 |
Indisulam |
| Molecular glue; pre-mRNA splicing modulator |
5509 |
IPTG |
| Used in cloning procedures with X-GAL |
6146 |
LAP |
| Photocrosslinker for hydrogels |
5427 |
D-Luciferin sodium salt |
| Firefly luciferase substrate |
5224 |
MTT |
| Reagent used in the measurement of cell proliferation |
5515 |
NADPH reduced form tetrasodium salt |
| Cofactor for many anabolic enzymes |
7004 |
NAI |
| Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable |
7391 |
O-Propargyl-puromycin |
| Puromycin analog for labeling newly synthesized proteins |
7974 |
P3S |
| Reagent for modifying RNA at 2'-OH position, for SHAPE-MAP experiments |
7854 |
PEI STAR™ transfection reagent |
| Polyethylenimine (PEI) transfection reagent, chemically-defined |
8174 |
PEI STAR-Go™ transfection reagent New |
| Aqueous solution of polyethylenimine (PEI) transfection reagent |
7739 |
Polyamine Supplement x1000 (lyophilized) |
| Media supplement; used as component of CEPT cocktail to enhance stem cell viability |
7711 |
Polybrene |
| DNA transfection enhancer |
7806 |
preQ1-alkyne |
| preQ1 with alkyne handle for click chemistry |
7833 |
preQ1-azide |
| preQ1 with azide handle for click chemistry |
7804 |
preQ1-biotin |
| PreQ1 with biotin handle for RNA labeling and purification |
5500 |
Protease Inhibitor Cocktail I |
| Protease inhibitor cocktail for mammalian cells |
8098 |
ProtiFect STAR™ Protein Transfection Reagent |
| Protein transfection reagent |
1292 |
Rapamycin |
| Chemical dimerizer; also mTOR inhibitor |
7723 |
RGD peptide |
| Directs association of cells with diverse biomaterials and surfaces |
7302 |
Sulfo-NHS-LC-Biotin |
| Amine reactive biotinylation reagent, cell impermeable |
7788 |
TBIA |
| Bivalent SHAPE cross-linking reagent |
7862 |
TBTA |
| Click chemistry auxiliary reagent; stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reaction |
7005 |
4-Thiouridine |
| Photoreactive uridine analog for RNA sequencing |
7863 |
THPTA |
| Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction |
6555 |
TokeOni |
| NIR-emission luciferin analog; ideal for deep tissue applications; orally bioavailable and brain penetrant |
4309 |
TPEN |
| Cell-permeable Zn2+ chelator; also inhibits RNA binding protein Lin28 |