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B-HT 933 dihydrochloride

Cat. No. 2758 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Selective α2 agonist
别名： Azepexole
化学名： 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for B-HT 933 dihydrochloride

B-HT 933 dihydrochloride is a selective α2-adrenoceptor agonist. Exhibits greater than 300-fold selectivity for the α2-adrenoceptor over the α1-adrenoceptor.

化合物库 for B-HT 933 dihydrochloride

B-HT 933 dihydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for B-HT 933 dihydrochloride

分子量 254.16
公式 C9H15N3O.2HCl
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 36067-72-8
PubChem ID 169743
InChI Key HBLPYIOKPJVFQW-UHFFFAOYSA-N
Smiles CCN1CCC(OC(N)=N2)=C2CC1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for B-HT 933 dihydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 25.42 100
DMSO 12.71 50

制备储备液 for B-HT 933 dihydrochloride

以下数据基于产品分子量 254.16。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.93 mL 19.67 mL 39.35 mL
5 mM 0.79 mL 3.93 mL 7.87 mL
10 mM 0.39 mL 1.97 mL 3.93 mL
50 mM 0.08 mL 0.39 mL 0.79 mL

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产品说明书 for B-HT 933 dihydrochloride

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for B-HT 933 dihydrochloride

参考文献是支持产品生物活性的出版物。

Bill et al (1989) The thermogenic actions of α2-adrenoceptor agonists in reserpinized mice are mediated via a central postsynaptic α2-adrenoceptor mechanism. Br.J.Pharmacol. 96 133 PMID: 2564288

Parkinson and Hughes (1995) The mechanism of action of α2-adrenoceptors in human isolated subcutaneous resistance arteries. Br.J.Pharmacol. 115 1463 PMID: 8564206

Kobinger and Pichler (1977) Pharmacological characterization of B-HT 933 (2-amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazolo-[5,4-d]-azepindihydrochloride) as a hypotensive agent of the "clonidine-type". Naunyn-Schmied.Arch.Pharmacol. 300 39 PMID: 22821

If you know of a relevant reference for B-HT 933 dihydrochloride, please let us know.

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关键词: B-HT 933 dihydrochloride, B-HT 933 dihydrochloride supplier, B-HT933, dihydrochloride, azepexole, alpha2, α2, a2, adrenoceptors, agonists, selective, adrenergic, receptors, Azepexole, Adrenergic, Alpha-2, Receptors, 2758, Tocris Bioscience

1 篇 B-HT 933 dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 B-HT 933 dihydrochloride 的部分引用包括：

Hamby et al (2012) Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. Toxins (Basel) 32 14489 PMID: 23077035

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