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B2

Cat. No. 2855 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2855 has been discontinued.

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说明： Promotes inclusion formation in Huntington's and Parkinson's diseases
别名： CPNQ
化学名： 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for B2

B2 is a promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease. Prevents mutant huntingtin-mediated proteasome dysfunction and reduces α-synuclein-mediated toxicity.

技术数据 for B2

分子量 396.83
公式 C20H17ClN4O3
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 115687-05-3
PubChem ID 3953303
InChI Key KLNPVNZJCWIQSK-UHFFFAOYSA-N
Smiles O=C(C4=CC=C(Cl)C=C4)N(CC3)CCN3C1=C(C=CC=N2)C2=C([N+]([O-])=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for B2

参考文献是支持产品生物活性的出版物。

Bodner et al (2006) Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parksinson's diseases. Proc.Natl.Acad.Sci.USA 103 4246

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关键词: B2, B2 supplier, Promotes, inclusion, formation, Huntingtons, Parkinsons, parkinson's, diseases, Huntingdons, Neuronal, Metabolism, Huntington's, CPNQ, Miscellaneous, Compounds, 2855, Tocris Bioscience

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