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Submit Review[bAla8]-Neurokinin A(4-10) is a NK2 receptor agonist (pD2 = 6.91). Produces bladder contraction and bronchospasm in guinea pigs in vivo.
分子量 | 780.93 |
公式 | C35H56N8O10S |
序列 |
DSFVALM (Modifications: Ala-5 = β-Ala, Met-7 = C-terminal amide) |
储存 | Desiccate at -20°C |
CAS Number | 122063-01-8 |
PubChem ID | 9987795 |
InChI Key | CKNPSJOMUQBPLA-WTWMNNMUSA-N |
Smiles | [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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参考文献是支持产品生物活性的出版物。
Carini et al (2001) Tachykinin NK2 receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study. Br.J.Pharmacol. 133 1107 PMID: 11487522
Maggi et al (1990) In vivo pharmacology of [βAla8]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist. Eur.J.Pharmacol. 177 81 PMID: 2160369
Rovero et al (1989) A potent and selective agonist for NK-2 tachykinin receptor. Peptides 10 593 PMID: 2550911
关键词: [bAla8]-Neurokinin A(4-10), [bAla8]-Neurokinin A(4-10) supplier, NK2, agonists, Tachykinin, Receptors, Neurokinin, MEN10210, MEN, 10210, Receptor, 1640, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 [bAla8]-Neurokinin A(4-10) 的部分引用包括:
Cavalcanti-de-Albuquerque et al (2019) Regulation of substrate utilization and adiposity by Agrp neurons. Nat Commun 10 311 PMID: 30659173
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