Bazedoxifene acetate

Name: Bazedoxifene acetate
Brand: Tocris Bioscience
SKU: 5263

Cat. No. 5263 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5263 has been discontinued.

View all Estrogen and Related Receptors products.

说明： Potent and selective estrogen receptor modulator (SERM)

化学名： 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate

纯度： ≥98% (HPLC)

说明书

引用文献

通路 (1)

生物活性技术数据说明书参考文献

生物活性 for Bazedoxifene acetate

Bazedoxifene acetate is a potent selective estrogen receptor modulator (SERM) (IC₅₀ values are 26 and 99 nM for ERα and ERβ respectively). Inhibits 17β-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat. No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium.

许可信息

Sold for research purposes under agreement from Pfizer Inc.

化合物库 for Bazedoxifene acetate

Bazedoxifene acetate is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Bazedoxifene acetate

分子量	530.65
公式	C₃₀H₃₄N₂O₃.C₂H₄O₂
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	198481-33-3
PubChem ID	154256
InChI Key	OMZAMQFQZMUNTP-UHFFFAOYSA-N
Smiles	CC2=C(C3=CC=C(O)C=C3)N(CC4=CC=C(OCCN5CCCCCC5)C=C4)C1=CC=C(O)C=C12.OC(C)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Bazedoxifene acetate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Bazedoxifene acetate

参考文献是支持产品生物活性的出版物。

Komm et al (2005) Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology 146 3999 PMID: 15961563

按标靶查看相关产品

Estrogen and Related Receptors

关键词: Bazedoxifene acetate, Bazedoxifene acetate supplier, selective, estrogen, receptors, modulator, SERM, for, ERα, Estrogen, and, Related, Receptors, 5263, Tocris Bioscience

篇 Bazedoxifene acetate 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Bazedoxifene acetate 的引用文献。