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BCH

Cat. No. 5027 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： LAT1 inhibitor
化学名： 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for BCH

BCH is an inhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines.

技术数据 for BCH

分子量 155.2
公式 C8H13NO2
储存 Store at RT
CAS Number 20448-79-7
PubChem ID 115288
InChI Key MPUVBVXDFRDIPT-UHFFFAOYSA-N
Smiles NC1(C(O)=O)CC2CCC1C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for BCH

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 15.52 100

制备储备液 for BCH

以下数据基于产品分子量 155.2。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 6.44 mL 32.22 mL 64.43 mL
5 mM 1.29 mL 6.44 mL 12.89 mL
10 mM 0.64 mL 3.22 mL 6.44 mL
50 mM 0.13 mL 0.64 mL 1.29 mL

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产品说明书 for BCH

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for BCH

参考文献是支持产品生物活性的出版物。

Kim et al (2008) BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. Biol.Pharm.Bull. 31 1096 PMID: 18520037

Lin et al (2004) L-type amino acid transporter-1 overexpression and melp. sensitivity in Barrett's adenocarcinoma. Neoplasia 6 74 PMID: 15068672

Fraga et al (2002) L-type amino acid transporters in two intestinal epithelial cell lines function as exchangers with neutral amino acids. J.Nutr. 132 733 PMID: 11925469

If you know of a relevant reference for BCH, please let us know.

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关键词: BCH, BCH supplier, LAT1, L-type, amino, acid, transporters, inhibitors, inhibits, Other, Ion, Pumps/Transporters, 5027, Tocris Bioscience

1 篇 BCH 的引用文献

引用文献是使用了 Tocris 产品的出版物。 BCH 的部分引用包括：

Ying et al (2005) Comparison of the biological activities of anagrelide and its major metabolites in haematopoietic cell cultures. Br J Pharmacol 146 324-32 PMID: 16041400

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