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说明： Bombesin antagonist
别名： [D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2
生物活性 for BIM 189
BIM 189 is a bombesin antagonist that reduces bombesin-induced satiety.
技术数据 for BIM 189
| 分子量 | 1137.73 |
| 公式 | C56H73ClN14O10 |
| 序列 |
FQWAVGHLF (Modifications: Phe-1 = D-Phe, Phe-9 = 4-Cl-Phe & C-terminal amide) |
| 储存 | Store at -20°C |
| CAS Number | 142062-55-3 |
| PubChem ID | 5748499 |
| InChI Key | XJWMPWLZAVKSPK-UYBYNCNQSA-N |
| Smiles | [H]N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(Cl)C=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BIM 189
参考文献 for BIM 189
参考文献是支持产品生物活性的出版物。
Coy et al (1990) Short chain bombesin pseudopeptides with potent bombesin receptor antagonist activity in rat and guinea pig acinar cells. Eur.J.Pharmacol. 190 31 PMID: 1963850
Laferrere et al (1992) Effects of bombesin, of a new bombesin agonist (BIM187) and a new antagonist (BIM189) on food intake in rats, in relation to cholecystokinin. Eur.J.Pharmacol. 215 23 PMID: 1516647
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关键词: BIM 189, BIM 189 supplier, Bombesin, antagonists, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, BIM189, [D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2, 2717, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.