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BIX

Cat. No. 5375 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5375 has been discontinued.

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说明： BiP (Hsp70-5) ER chaperone inducer
化学名： 2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid
纯度： ≥98% (HPLC)
说明书
引用文献
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文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for BIX

BIX is a BiP (Hsp70-5) ER chaperone inducer; induces BiP expression in vitro and in vivo. Protects against ER-stress induced cell death in neuronal and retinal cell lines. Also protects against ischaemia-induced hippocampal cell death in vivo.

技术数据 for BIX

分子量 209.22
公式 C9H7NO3S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 101714-41-4
PubChem ID 16656807
InChI Key SVFLBLCWKKQKDW-UHFFFAOYSA-N
Smiles O=C(CSC#N)C1=CC=C(O)C(O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BIX

参考文献是支持产品生物活性的出版物。

Inokuchi et al (2009) Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death. Invest.Ophthalmol.Vis.Sci. 50 334 PMID: 18757512

Oida et al (2008) Induction of BiP, an ER-resident protein, prevents the neuronal death induced by transient forebrain ischemia in gerbil. Brain Res. 1208 217 PMID: 18395193

Kudo et al (2008) A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ. 15 364 PMID: 18049481

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关键词: BIX, BIX supplier, BIP, ER, endoplasmic, reticulum, chaperones, inducers, stress, binding, immunoglobulin, protein, Hsp70, Other, stress/UPR, 5375, Tocris Bioscience

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