Other ER Stress/UPR

Other ER Stress/UPR Inhibitors
Cat. No.	Product Name / Activity
5141	AZD 5582 dihydrochloride
	Dimeric Smac mimetic; potent IAP inhibitor
6955	Ceapin A7
	Selective inhibitor of ATF6α; sensitizes cells to ER stress
3922	Eeyarestatin I
	Potent inhibitor of ER-associated protein degradation and translocation
5284	trans-ISRIB
	Integrated stress response (ISR) inhibitor
5153	ML 240
	ATP-competitive inhibitor of p97 ATPase
6180	NMS 873
	Potent and selective p97 ATPase (VCP) allosteric inhibitor
2347	Salubrinal
	Selective inhibitor of eIF2a dephosphorylation
4825	TC ASK 10
	Potent and selective ASK1 inhibitor; orally bioavailable
4686	Xanthohumol
	p97 ATPase (VCP) inhibitor
Substrates
Cat. No.	Product Name / Activity
4515	2-Deoxy-D-glucose
	Enhances chimeric antigen receptor T cell activity. Disrupts N-glycan expression
Other ER Stress/UPR Activators
Cat. No.	Product Name / Activity
1231	Brefeldin A
	Disrupts Golgi apparatus resulting in activation of ER stress pathways
5869	CDN 1163
	SERCA2 allosteric activator
7192	SMIP 004
	S-phase kinase-associated protein 2 (SKP2) inhibitor; activates UPR
Other
Cat. No.	Product Name / Activity
6759	AA 147
	ER proteostasis regulator
1072	AGN 192403 hydrochloride
	Binds TMED9 cargo receptor; releases mutant MUC-1 from vesicles and promotes trafficking to lysosome fro degradation
6116	BHPI
	Activates unfolded protein response; also ERα antagonist