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BML 111

Cat. No. 5488 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： FPR2 (lipoxin A4 receptor) agonist
化学名： (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for BML 111

BML 111 is a FPR2 (lipoxin A4 receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A4 analog.

技术数据 for BML 111

分子量 192.21
公式 C8H16O5
储存 Store at -20°C
CAS Number 78606-80-1
PubChem ID 10899465
InChI Key RNMFWAFZUNVQOR-NKWVEPMBSA-N
Smiles OC[C@@H](O)[C@@H](O)CCCC(OC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for BML 111

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 19.22 100
DMSO 19.22 100

制备储备液 for BML 111

以下数据基于产品分子量 192.21。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 5.2 mL 26.01 mL 52.03 mL
5 mM 1.04 mL 5.2 mL 10.41 mL
10 mM 0.52 mL 2.6 mL 5.2 mL
50 mM 0.1 mL 0.52 mL 1.04 mL

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参考文献 for BML 111

参考文献是支持产品生物活性的出版物。

Chen et al (2010) Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis. Mol.Cancer.Ther. 9 2164 PMID: 20682645

Gong et al (2012) BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats. Resuscitation. 83 907 PMID: 22245750

If you know of a relevant reference for BML 111, please let us know.

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关键词: BML 111, BML 111 supplier, BML111, formyl, peptide, receptors, FPR2, agonists, agonism, lipoxinA4, LPA4, Formyl, Peptide, Receptors, 5488, Tocris Bioscience

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