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Bombinakinin M

Cat. No. 2371 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2371 has been discontinued.

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说明： Potent bradykinin agonist
别名： Maximakinin
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Bombinakinin M

Bombinakinin M is a potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth muscle of guinea pig ileum (EC50 = 4.0 nM).

技术数据 for Bombinakinin M

分子量 2179.55
公式 C100H159N31O24
序列 DLPKINRKGPRPPGFSPFR
储存 Desiccate at -20°C
CAS Number 509151-65-9
PubChem ID 90473828
InChI Key ZEEWOWMYALYVCG-UOGIEMGNSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Bombinakinin M

参考文献是支持产品生物活性的出版物。

Lai et al (2001) A novel bradykinin-related peptide from skin secretions of toad Bombina maxima and its precursor containing six identicals copies of the final product. Biochem.Biophys.Res.Comm. 286 259

O'Rourke et al (2004) The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima. Regul.Peptides 121 65

Lee et al (2005) Cloning of bradykinin precursor cDNAs from skin of Bombina maxima reveals novel bombinakinin M antagonists and a bradykinin potential peptide. Regul.Peptides 127 207

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关键词: Bombinakinin M, Bombinakinin M supplier, Potent, bradykinin, receptor, agonists, B1, B2, Receptors, Bradykinin, BombinakininM, Maximakinin, 2371, Tocris Bioscience

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