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Submit ReviewBradykinin
说明： Endogenous agonist at bradykinin receptors (B2 > B1)
纯度： ≥95% (HPLC)
生物活性 for Bradykinin
Bradykinin is an endogenous bradykinin receptor agonist that displays selectivity for B2 over B1 receptors. Proinflammatory peptide.
技术数据 for Bradykinin
| 分子量 | 1060.22 |
| 公式 | C50H73N15O11 |
| 序列 | RPPGFSPFR |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 58-82-2 |
| PubChem ID | 439201 |
| InChI Key | QXZGBUJJYSLZLT-FDISYFBBSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Bradykinin
| 溶解性 | Soluble to 1 mg/ml in water |
产品说明书 for Bradykinin
参考文献 for Bradykinin
参考文献是支持产品生物活性的出版物。
Regoli et al (1998) Bradykinin receptors and their antagonists. Eur.J.Pharmacol. 348 1 PMID: 9650825
Leeb-Lundberg et al (2005) International union of pharmacology XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol.Rev. 57 27 PMID: 15734727
Abraham et al (2006) Peptide and non-peptide bradykinin receptor antagonists: role in allergic airway disease Eur.J.Pharmacol. 533 215 PMID: 16455073
If you know of a relevant reference for Bradykinin, please let us know.
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关键词: Bradykinin, Bradykinin supplier, Endogenous, agonists, bradykinin, receptors, B2, B1, Receptors, Bradykinin, 3004, Tocris Bioscience
7 篇 Bradykinin 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Bradykinin 的部分引用包括：
Hannedouche et al (2013) Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells. Proc Natl Acad Sci U S A 288 27434 PMID: 23940034
Zhou et al (2019) Serum bradykinin levels as a diagnostic marker in cervical cancer with a potential mechanism to promote VEGF expression via BDKRB2. Int J Oncol 55 131 PMID: 31059006
Zhang (2019) Direct Gαq Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor Activation. Cell Rep 27 3672 PMID: 31216483
Jakubowska et al (2016) Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation. Open Biol. 6 160149 PMID: 27488376
Kirkby et al (2012) Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system. Gastroenterology 109 17597 PMID: 23045674
Zakaria et al (2014) Antinociceptive activity of methanolic extract of Muntingia calabura leaves: further elucidation of the possible mechanisms. BMC Complement Altern Med 14 63 PMID: 24555641
Bell et al (2014) Retinal vasculature of adult zebrafish: in vivo imaging using confocal scanning laser ophthalmoscopy. Exp Eye Res 129 107 PMID: 25447564
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