BRL 15572 hydrochloride

Name: BRL 15572 hydrochloride
Brand: Tocris Bioscience
SKU: 1207

Cat. No. 1207 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1207 has been discontinued.

View all 5-HT<sub>1D</sub> Receptors products.

说明： Selective h5-HT_1D antagonist

化学名： 3-[4-(4-Chlorophenyl)piperazin-1-yl]-1,1-diphenyl-2-propanol hydrochloride

说明书

引用文献 (3)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for BRL 15572 hydrochloride

BRL 15572 hydrochloride is a selective h5-HT_1D antagonist, displaying 60-fold selectivity over h5-HT_1B, and exhibiting little or no affinity for a range of other receptor types.

许可信息

Sold with the permission of GlaxoSmithKline

技术数据 for BRL 15572 hydrochloride

分子量	443.42
公式	C₂₅H₂₇ClN₂O.HCl
储存	Desiccate at +4°C
CAS Number	1173022-77-9
PubChem ID	11957475
InChI Key	KQGJIKWDFWLCHO-UHFFFAOYSA-N
Smiles	Cl.OC(CN1CCN(CC1)C1=CC=CC(Cl)=C1)C(C1=CC=CC=C1)C1=CC=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for BRL 15572 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for BRL 15572 hydrochloride

参考文献是支持产品生物活性的出版物。

Hagan et al (1997) Stimulation of 5-HT_1B receptors causes hypothermia in the rat. Eur.J.Pharmacol. 331 169 PMID: 9274976

Price et al (1997) SB-216641 and BRL-15572 - compounds to pharmacologically discriminate h5-HT_1B and h5-HT_1D receptors. Naunyn Schmiedebergs Arch.Pharmacol. 356 312 PMID: 9303567

Saxena et al (1998) 5-HT₁-like receptors: a time to bid goodbye. TiPS 19 311 PMID: 9745358

Schlicker et al (1997) Effects of selective h5-HT_1B (SB-216641) and h5-HT_1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors. Naunyn Schmiedebergs Arch.Pharmacol. 356 321 PMID: 9303568

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关键词: BRL 15572 hydrochloride, BRL 15572 hydrochloride supplier, Selective, h5-HT1D, antagonist, Serotonin, Receptors, BRL15572, hydrochloride, GlaxoSmithKline, GSK, 5-HT1D, 1207, Tocris Bioscience

3 篇 BRL 15572 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 BRL 15572 hydrochloride 的部分引用包括：

Baillie et al (2012) Sumatriptan inhibition of N-type calcium channel mediated signaling in dural CGRP terminal fibres. World J Gastroenterol 63 362 PMID: 22691374

Hampson et al (2007) Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. Diabetologia 50 1743 PMID: 17579833

McDaid and Docherty (2001) Vascular actions of MDMA involve alpha1 and alpha2-adrenoceptors in the anaesthetized rat. Br J Pharmacol 133 429 PMID: 11375260