Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewPotent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively).
分子量 | 252.27 |
公式 | C15H12N2O2 |
储存 | Desiccate at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 1104546-89-5 |
PubChem ID | 25113764 |
InChI Key | BTYSIDSTHDDAJW-LCYFTJDESA-N |
Smiles | O=C(NC3=O)C1=CC=CC=C1/C3=C/C2=CC=CN2C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Eltze et al (2008) Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol.Pharmacol. 74 1587 PMID: 18809672
关键词: BYK 204165, BYK 204165 supplier, BYK204165, PARP1, poly(ADP-ribose), polymerases, selective, inhibitors, inhibits, Poly(ADP-ribose), Polymerase, 3734, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 BYK 204165 的部分引用包括:
Hallett et al (2016) Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma. Mol Oncol 10 1461 PMID: 27599694
Hamilton (2014) Cytotoxic effects of fascaplysin against small cell lung cancer cell lines. Lab Chip 12 1377 PMID: 24608973
目前没有该产品的评论。 Be the first to review BYK 204165 and earn rewards!
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:
In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. This poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.