BYK 204165

Discontinued Product

3734 has been discontinued.

View all Poly(ADP-ribose) Polymerase products.
说明: Selective PARP-1 inhibitor
化学名: 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione
纯度: ≥99% (HPLC)
说明书
引用文献 (2)
评论
文献 (2)

生物活性 for BYK 204165

Potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively).

技术数据 for BYK 204165

分子量 252.27
公式 C15H12N2O2
储存 Desiccate at +4°C
纯度 ≥99% (HPLC)
CAS Number 1104546-89-5
PubChem ID 25113764
InChI Key BTYSIDSTHDDAJW-LCYFTJDESA-N
Smiles O=C(NC3=O)C1=CC=CC=C1/C3=C/C2=CC=CN2C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for BYK 204165

参考文献是支持产品生物活性的出版物。

Eltze et al (2008) Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol.Pharmacol. 74 1587 PMID: 18809672

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关键词: BYK 204165, BYK 204165 supplier, BYK204165, PARP1, poly(ADP-ribose), polymerases, selective, inhibitors, inhibits, Poly(ADP-ribose), Polymerase, 3734, Tocris Bioscience

2 篇 BYK 204165 的引用文献

引用文献是使用了 Tocris 产品的出版物。 BYK 204165 的部分引用包括:

Hallett et al (2016) Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma. Mol Oncol 10 1461 PMID: 27599694

Hamilton (2014) Cytotoxic effects of fascaplysin against small cell lung cancer cell lines. Lab Chip 12 1377 PMID: 24608973


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