C-type natriuretic peptide (1-22) (human, rat, swine)

Name: C-type natriuretic peptide (1-22) (human, rat, swine)
Brand: Tocris Bioscience
SKU: 3520
Rating: 5 (1 reviews)

Cat. No. 3520 4 篇引用文献 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Endogenous peptide agonist at NPR2

纯度： ≥95% (HPLC)

说明书

引用文献 (4)

生物活性技术数据溶解性计算器说明书参考文献

生物活性

C-type natriuretic peptide (1-22) (human, rat, swine) is an endogenous peptide found in plasma and cerebrospinal fluid. Behaves as an agonist at natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). Inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo.

技术数据

分子量	2197.61
公式	C₉₃H₁₅₇N₂₇O₂₈S₃
序列	GLSKGCFGLKLDRIGSMSGLGC (Modifications: Disulfide bridge: 6-22)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	127869-51-6
PubChem ID	16179407
InChI Key	UHSBKBYWHCBDCJ-DYGWFTAGSA-N
Smiles	[H]NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据

溶解性	Soluble to 1 mg/ml in water

产品说明书

分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Suga et al (1992) Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology 130 229 PMID: 1309330

Pejchalova et al (2007) C-natriuretic peptide: An important regulator of cartilage. Mol.Genet.Metab. 92 210 PMID: 17681481

Rose and Giles (2008) Natriuretic peptide C receptor signalling in the heart and vasculature. J.Physiol. 586 353 PMID: 18006579

If you know of a relevant reference for C-type natriuretic peptide (1-22) (human, rat, swine), please let us know.

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关键词: C-type natriuretic peptide (1-22) (human, rat, swine), C-type natriuretic peptide (1-22) (human, rat, swine) supplier, Endogenous, peptide, agonists, NPR2, ANP, Receptors, Atrial, Natriuretic, Peptide, Receptor, 3520, Tocris Bioscience

4 篇 C-type natriuretic peptide (1-22) (human, rat, swine) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 C-type natriuretic peptide (1-22) (human, rat, swine) 的部分引用包括：

Hui et al (2021) Coordinated Formation of IMPDH2 Cytoophidium in Mouse Oocytes and Granulosa Cells. Front Cell Dev Biol 9 690536 PMID: 34124077

Zhen et al (2021) C-Type Natriuretic Peptide Ameliorates Vascular Injury and Improves Neurological Outcomes in Neonatal Hypoxic-Ischemic Brain Injury in Mice. Int J Mol Sci 22 PMID: 34445671

Stott et al (2015) Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats. Hypertension 65 676 PMID: 25547342

Lubo et al (2023) 3D doppler ultrasound imaging of cerebral blood flow for assessment of neonatal hypoxic-ischemic brain injury in mice. PLoS One 18 e0285434 PMID: 37159455

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