Cannabigerol

Cat. No. 3021 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Cannabinoid receptor partial agonist

化学名： 2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol

纯度： ≥95% (HPLC)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Cannabigerol

Cannabigerol is a partial agonist of CB₂ and CB₁ receptors (K_i values are 337 and 440 nM respectively). Also exhibits α₂-adrenoceptor agonist activity (EC₅₀ = 0.2 nM in mouse brain membranes).

技术数据 for Cannabigerol

分子量	316.48
公式	C₂₁H₃₂O₂
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	25654-31-3
PubChem ID	5315659
InChI Key	QXACEHWTBCFNSA-SFQUDFHCSA-N
Smiles	OC(C=C(CCCCC)C=C1O)=C1C/C=C(C)/CC/C=C(C)\C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Cannabigerol

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	ethanol	31.65	100
	DMSO	31.65	100

制备储备液 for Cannabigerol

以下数据基于产品分子量 316.48。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.16 mL	15.8 mL	31.6 mL
5 mM	0.63 mL	3.16 mL	6.32 mL
10 mM	0.32 mL	1.58 mL	3.16 mL
50 mM	0.06 mL	0.32 mL	0.63 mL

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产品说明书 for Cannabigerol

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Cannabigerol

参考文献是支持产品生物活性的出版物。

Gauson et al (2007) Cannabigerol behaves as a partial agonist at both CB₁ and CB₂ receptors. Symposium on the Cannabinoids 206

Pertwee The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br.J.Pharmacol. 153 199 PMID: 17828291

Cascio et al (2010) Evidence that the plant cannabinoid cannabigerol is a highly potent α₂-adrenoceptor agonist and moderately potent 5HT_1A receptor antagonist. Br.J.Pharmacol. 159 129 PMID: 20002104

If you know of a relevant reference for Cannabigerol, please let us know.

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关键词: Cannabigerol, Cannabigerol supplier, phytocannabinoids, cbg, cannabigerol, cb1, cb2, partial, agonists, alpha2, α2, a2-adrenoceptors, adrenergics, receptors, Non-selective, Cannabinoids, 3021, Tocris Bioscience

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Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.