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Submit ReviewCarmoxirole hydrochloride
说明： Selective, peripherally acting D2-like agonist
别名： EMD 45609
化学名： 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride
纯度： ≥98% (HPLC)
生物活性 for Carmoxirole hydrochloride
Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo.
技术数据 for Carmoxirole hydrochloride
| 分子量 | 410.94 |
| 公式 | C24H26N2O2.HCl |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 115092-85-8 |
| PubChem ID | 9822866 |
| InChI Key | LRJUHOBITQUXIO-UHFFFAOYSA-N |
| Smiles | Cl.OC(=O)C1=CC=C2NC=C(CCCCN3CCC(=CC3)C3=CC=CC=C3)C2=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Carmoxirole hydrochloride
参考文献 for Carmoxirole hydrochloride
参考文献是支持产品生物活性的出版物。
Haeusler et al (1992) Pharmacological basis for antihypertensive therapy with a novel DA agonist Eur.Heart J. 13 129 PMID: 1356783
Rump et al (1993) DA receptor modulation of noradrenaline release by carmoxirole in human cortical kidney slices. Eur.J.Clin.Pharmacol. 44 S47 PMID: 8097997
Hasse et al (1991) Neurochemical profile of EMD 45609 (carmoxirole), a DA DA2-receptor agonist. Naunyn-Schmied.Arch.Pharmacol. 343 588
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关键词: Carmoxirole hydrochloride, Carmoxirole hydrochloride supplier, Selective, peripherally, peripheral, D2-like, agonists, Dopamine, Non-Selective, Receptors, dopaminergic, EMD45609, EMD, 45609, Non-selective, 2193, Tocris Bioscience
2 篇 Carmoxirole hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Carmoxirole hydrochloride 的部分引用包括：
Schlenker and Schultz (2012) Hypothyroidism stimulates D2 receptor-mediated breathing in response to acute hypoxia and alters D2 receptors levels in carotid bodies and brain. Respir Physiol Neurobiol 180 69 PMID: 22051191
Schlenker et al (2014) Hypothyroidism affects D2 receptor-mediated breathing without altering D2 receptor expression. Respir Physiol Neurobiol 193 29 PMID: 24434437
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Dopamine Receptors Scientific Review
Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
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