主页 / 药理学 / GPCRs / 7-TM Receptors / Cannabinoid Receptors / CB2 Receptors / CB2 Receptor Agonists / CB 65

CB 65

Cat. No. 2663 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： High affinity, selective CB2 agonist
化学名： N-Cyclohexyl-7-chloro-1-[2-(4-morpholinyl)ethyl]quinolin-4(1H)-one-3-carboxamide
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for CB 65

CB 65 is a high affinity and selective CB2 receptor agonist; Ki values are 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.

技术数据 for CB 65

分子量 417.93
公式 C22H28ClN3O3
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 913534-05-1
PubChem ID 16086891
InChI Key MFKWLGOHFQBVAA-UHFFFAOYSA-N
Smiles ClC1=CC=C2C(N(CCN3CCOCC3)C=C(C(NC4CCCCC4)=O)C2=O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for CB 65

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 2.09 5 温和加热

制备储备液 for CB 65

以下数据基于产品分子量 417.93。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.05 mM 47.85 mL 239.27 mL 478.55 mL
0.25 mM 9.57 mL 47.85 mL 95.71 mL
0.5 mM 4.79 mL 23.93 mL 47.85 mL
2.5 mM 0.96 mL 4.79 mL 9.57 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for CB 65

参考文献是支持产品生物活性的出版物。

Manera et al (2006) Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists. J.Med.Chem. 49 5947 PMID: 17004710

If you know of a relevant reference for CB 65, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 CB2 Receptor Agonists

关键词: CB 65, CB 65 supplier, High, affinity, selective, CB2, agonists, cannabinoids, Receptors, CB65, cb2r, 2663, Tocris Bioscience

1 篇 CB 65 的引用文献

引用文献是使用了 Tocris 产品的出版物。 CB 65 的部分引用包括：

Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888

您是否知道使用了 Tocris CB 65 的优秀论文？ 请告知我们.

CB 65 的评论

目前没有该产品的评论。 Be the first to review CB 65 and earn rewards!

Have you used CB 65?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.