CDP 840 hydrochloride

Name: CDP 840 hydrochloride
Brand: Tocris Bioscience
SKU: 3936

Cat. No. 3936 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3936 has been discontinued.

View all Phosphodiesterases products.

说明： Potent and selective PDE4 inhibitor

化学名： 4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for CDP 840 hydrochloride

CDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase (PDE) 4 (IC₅₀ = 12 nM for native PDE4). Competitively inhibits all PDE4 isoenzymes (IC₅₀ values are 4, 9, 9 and 45 nM for PDE4A, PDE4B, PDE4C and PDE4D human recombinant isoforms expressed in yeast).

技术数据 for CDP 840 hydrochloride

分子量	409.95
公式	C₂₅H₂₇NO₂.HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
PubChem ID	89809670
InChI Key	DQXFOLCDYKWSIT-GNAFDRTKSA-N
Smiles	COC1=C(OC2CCCC2)C=C([C@@H]([C@]4=CC=CC=C4)CC3=CC=NC=C3)C=C1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for CDP 840 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for CDP 840 hydrochloride

参考文献是支持产品生物活性的出版物。

Hughes et al (1996) The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4. Br.J.Pharmacol. 118 1183 PMID: 8818342

Perry et al (1998) CDP840: a novel inhibitor of PDE-4. Cell Biochem.Biophys. 29 113 PMID: 9631241

Cooper et al (1999) A comparison of the inhibitory activity of PDE4 inhibitors on leukocyte PDE4 activity in vitro and eosinophil trafficking in vivo. Br.J.Pharmacol. 126 1863 PMID: 10372831

按标靶查看相关产品

Phosphodiesterases

按产品操作查看相关产品

查看全部 Phosphodiesterase Inhibitors

关键词: CDP 840 hydrochloride, CDP 840 hydrochloride supplier, CDP840, hydrochloride, phosphodiesterases, pde4, isoenzymes, inhibitors, inhibits, potent, selective, 162542-90-7, Phosphodiesterases, 3936, Tocris Bioscience

篇 CDP 840 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 CDP 840 hydrochloride 的引用文献。