Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewCGRP 8-37 (human)
说明： CGRP antagonist
别名： Calcitonin Gene-Related Peptide 8-37 (human)
纯度： ≥95% (HPLC)
生物活性 for CGRP 8-37 (human)
CGRP 8-37 (human) is a peptide antagonist for CGRP1 receptors.
技术数据 for CGRP 8-37 (human)
| 分子量 | 3125.64 |
| 公式 | C139H230N44O38 |
| 序列 |
VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF (Modifications: Phe-30 = C-terminal amide) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 119911-68-1 |
| PubChem ID | 16134896 |
| InChI Key | NDACAFBDTQIYCQ-YVQXRMNASA-N |
| Smiles | [H]N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for CGRP 8-37 (human)
| 溶解性 | Soluble to 0.50 mg/ml in water |
产品说明书 for CGRP 8-37 (human)
参考文献 for CGRP 8-37 (human)
参考文献是支持产品生物活性的出版物。
Nakamura et al (1998) Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 807 203 PMID: 9757038
Poyner (1995) Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 16 424 PMID: 8578616
Poyner et al (1998) Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides. Br.J.Pharmacol. 124 1659 PMID: 9756381
Wisskirchen et al (1998) Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br.J.Pharmacol. 123 1673 PMID: 9605575
If you know of a relevant reference for CGRP 8-37 (human), please let us know.
按产品操作查看相关产品
关键词: CGRP 8-37 (human), CGRP 8-37 (human) supplier, CGRP1, receptor, antagonists, CGRP, Receptors, AM1, AM2, calcitonin-gene, related, peptide, CGRP8-37, (human), Calcitonin, Gene-Related, Peptide, 8-37, and, Related, 1181, Tocris Bioscience
1 篇 CGRP 8-37 (human) 的引用文献
引用文献是使用了 Tocris 产品的出版物。 CGRP 8-37 (human) 的部分引用包括：
Fernandes et al (2016) Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner. World J Gastroenterol 18 7 PMID: 26754745
您是否知道使用了 Tocris CGRP 8-37 (human) 的优秀论文？ 请告知我们.
CGRP 8-37 (human) 的评论
目前没有该产品的评论。 Be the first to review CGRP 8-37 (human) and earn rewards!
Have you used CGRP 8-37 (human)?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.