Chaetoglobosin A

Name: Chaetoglobosin A
Brand: Tocris Bioscience
SKU: 5804
Rating: 5 (1 reviews)

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Discontinued Product

5804 has been discontinued.

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说明： Antibiotic; selectively induces apoptosis of CLL cells

化学名： (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-3H-cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Chaetoglobosin A

Chaetoglobosin A is an antibiotic; preferentially induces apoptosis in chronic lymphocytic leukemia (CLL) cells over normal B cells. Inhibits actin polymerization and leads to the accumulation of cells in G₂ phase.

技术数据 for Chaetoglobosin A

分子量	528.64
公式	C₃₂H₃₆N₂O₅
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	50335-03-0
PubChem ID	102601376
InChI Key	OUMWCYMRLMEZJH-VOXRAUTJSA-N
Smiles	O=C1[C@]23[C@]([H])([C@H](CC4=CNC5=CC=CC=C45)N1)[C@H](C)[C@]6(C)[C@]([H])([C@@]2(/C=C/C[C@H](C)/C=C(C)/[C@@H](O)C(/C=C/C3=O)=O)[H])O6

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Chaetoglobosin A

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Chaetoglobosin A

参考文献是支持产品生物活性的出版物。

Knudsen et al (2014) Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 28 1289 PMID: 24280868

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篇 Chaetoglobosin A 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Chaetoglobosin A 的引用文献。