Cinanserin hydrochloride

Name: Cinanserin hydrochloride
Brand: Tocris Bioscience
SKU: 0460

Cat. No. 0460 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0460 has been discontinued.

View all Non-selective 5-HT<sub>2</sub> products.

说明： Selective 5-HT₂ antagonist; also 3C-like proteinase inhibitor

化学名： N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenyl-2-propenamide hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献 (3)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Cinanserin hydrochloride

Cinanserin hydrochloride is a 5-HT₂ antagonist. Also inhibits 3C-like proteinase (3CL^pro; M^pro). Inhibits replication of SARS-CoV.

技术数据 for Cinanserin hydrochloride

分子量	376.94
公式	C₂₀H₂₄N₂OS.HCl
储存	Desiccate at RT
纯度	≥99% (HPLC)
CAS Number	54-84-2
PubChem ID	6433141
InChI Key	LXGJPDKYMJJWRB-IERUDJENSA-N
Smiles	O=C(/C=C/C2=CC=CC=C2)NC1=CC=CC=C1SCCCN(C)C.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Cinanserin hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Cinanserin hydrochloride

参考文献是支持产品生物活性的出版物。

Leysen et al (1981) Receptor binding profile of R-41-468, a novel antagonist at 5HT₂ receptors. Life Sci. 28 1015 PMID: 6261070

Pierce et al (1992) Molecular structure basis of ligand selectivity for 5-HT₂ versus 5-HT_1C cortical receptors. Naunyn Schmiedebergs Arch.Pharmacol. 346 4 PMID: 1407003

Chen et al (2005) Cinanserin is an inhibitor of the 3C-like proteinase of the severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. J.Virol. 79 7095 PMID: 15890949

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3 篇 Cinanserin hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Cinanserin hydrochloride 的部分引用包括：

Gautam et al (2016) Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling. Mol Cancer 15 75 PMID: 27871326

Buznikov et al (2010) A putative 'pre-nervous' endocannabinoid system in early echinoderm development. Dev Neurosci 32 1 PMID: 19907129

Seeburg et al (2004) Frequency-dependent modulation of retinogeniculate transmission by serotonin. J Neurosci 24 10950 PMID: 15574745