Other Proteases

Other Protease Inhibitors

Cat. No. Product Name / Activity
5402 6bK
Insulin degrading enzyme (IDE) inhibitor
5175 AEBSF
Broad spectrum, irreversible inhibitor of serine proteases
5491 Aliskiren hemifumarate
Potent renin inhibitor; antihypertensive
2511 APC 366
Tryptase inhibitor
4139 Aprotinin
Competitive serine protease inhibitor
1637 Argatroban
Potent thrombin inhibitor
3193 Camostat mesylate
Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells
2512 CGS 35066
Endothelin-converting enzyme (ECE) inhibitor
0460 Cinanserin hydrochloride
3C-like proteinase inhibitor; also selective 5-HT2 antagonist; antiviral
3501 Decanoyl-RVKR-CMK
Subtilisin/Kex2p-like proprotein convertase inhibitor
4524 EGCG
β-secretase (BACE) inhibitor; inhibits amyloid assembly
7496 FMK 9a
Potent ATG4B/autophagin-1 inhibitor; also inhibits calpain and cathepsin B
1798 Gabexate mesylate
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
6272 KYP 2047
High affinity prolyl oligopeptidase inhibitor; anti-angiogenic, neuroprotective and brain penetrant
2627 L-685,458
High affinity SPP inhibitor; also potent γ-secretase inhibitor
1167 Leupeptin hemisulfate
Inhibits trypsin-like/cysteine proteases
7081 LY 2886721 Hydrochloride
Potent and selective β-secretase (BACE) inhibitor
4848 MI 2 (MALT1 inhibitor)
MALT1 inhibitor
3081 Nafamostat mesylate
Serine protease inhibitor; inhibits tryptase
6423 Pep 2-8
Potent PCSK9 inhibitor
3354 PF 429242 dihydrochloride
Competitive inhibitor of SREBP site 1 protease
6333 Phosphoramidon disodium salt
Neutral endopeptidase and endothelin converting enzyme inhibitor
4486 PMSF
Non-selective protease inhibitor; also blocks anandamide metabolism
5772 Sacubitril calcium
Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
7659 Verubecestat
BACE1 and BACE2 inhibitor
5563 VTP 27999 trifluoroacetate
Highly potent and selective renin inhibitor

Substrates

Cat. No. Product Name / Activity
3791 Hemopressin (human, mouse)
Bioactive substrate for endopeptidase 24.15, neurolysin and ACE