Combretastatin A4

Name: Combretastatin A4
Brand: Tocris Bioscience
SKU: 1495

Cat. No. 1495 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1495 has been discontinued.

View all Antiangiogenics products.

说明： Antiangiogenic

别名： CRC 87-09,NSC 817373

化学名： 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol

纯度： ≥99%

说明书

引用文献 (2)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Combretastatin A4

Antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo. Inhibits tubulin polymerization.

技术数据 for Combretastatin A4

分子量	316.35
公式	C₁₈H₂₀O₅
储存	Desiccate at -20°C
纯度	≥99%
CAS Number	117048-59-6
PubChem ID	5351344
InChI Key	HVXBOLULGPECHP-WAYWQWQTSA-N
Smiles	OC1=CC(\C=C/C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Combretastatin A4

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Combretastatin A4

参考文献是支持产品生物活性的出版物。

Dorr et al (1996) Antitumor activity of combretastatin-A4 phosphate, a natural product tubulin inhibitor. Invest.New Drugs 14 131 PMID: 8913833

Griggs et al (2001) Potent anti-metastatic activity of combretastatin-A4. Int.J.Oncol. 19 821 PMID: 11562761

Lin et al (2007) Combretastatin A4-induced differential cytotoxicity and reduced metastatic ability by inhibition of AKT function in human gastric cancer cells. J.Pharmacol.Exp.Ther. 323 365 PMID: 17646428

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关键词: Combretastatin A4, Combretastatin A4 supplier, inhibitors, inhibits, tubulin, polymerization, Antitumor, antimetastatic, Antiangiogenics, Tau, Microtubules, Mitosis, CombretastatinA4, CRC87-09, NSC817373, CRC, 87-09, NSC, 817373, 1495, Tocris Bioscience

2 篇 Combretastatin A4 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Combretastatin A4 的部分引用包括：

Arora et al (2009) Novel microtubule polymerization inhibitor with potent antiproliferative and antitumor activity. J Biol Chem 69 1910 PMID: 19223556

Meseke et al (2018) Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin. Eneuro 5 PMID: 30406178