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Submit ReviewCP 135807
说明： Selective 5-HT1D agonist
化学名： 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine
纯度： ≥98% (HPLC)
生物活性 for CP 135807
Selective 5-HT1D receptor agonist. Produces dose-dependent decreases in extracellular 5-HT concentration.
许可信息
Sold for research purposes under agreement from Pfizer Inc.
技术数据 for CP 135807
| 分子量 | 351.4 |
| 公式 | C19H21N5O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 151272-90-1 |
| PubChem ID | 5487088 |
| InChI Key | YPFIYPNOWVPAPR-OAHLLOKOSA-N |
| Smiles | CN(CCC4)[C@H]4CC1=CNC2=C1C=C(NC3=NC=CC=C3[N+]([O-])=O)C=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for CP 135807
参考文献 for CP 135807
参考文献是支持产品生物活性的出版物。
Hertel et al (1999) The antipsychotic drug risper. interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex. Neuropharmacology 38 1175 PMID: 10462130
Mansbach et al (1996) CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology 128 313 PMID: 8972551
Rollema et al (1996) Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo. J.Neurochem. 67 2204 PMID: 8863532
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关键词: CP 135807, CP 135807 supplier, selective, 5-HT, serotonin, 5-HT1D, receptors, agonists, Pfizer, CP135807, Receptors, 3783, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.