Cytochalasin B

Cat. No. 5474 7 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Inhibitor of actin polymerization

化学名： (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione

纯度： ≥98% (HPLC)

引用文献 (7)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Cytochalasin B

Cytochalasin B is an inhibitor of actin polymerization. Inhibits cell division, migration and glucose transport. Causes G₂/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells. Cell permeable.

技术数据 for Cytochalasin B

分子量	479.61
公式	C₂₉H₃₇NO₅
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	14930-96-2
PubChem ID	5311281
InChI Key	GBOGMAARMMDZGR-TYHYBEHESA-N
Smiles	C=C([C@H]1C)[C@@H](O)[C@]([C@@]2(O3)[C@]1([H])[C@H](CC4=CC=CC=C4)NC2=O)([H])/C=C/C[C@H](C)CCC[C@@H](O)/C=C/C3=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Cytochalasin B

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	4.8	10 温和加热

制备储备液 for Cytochalasin B

以下数据基于产品分子量 479.61。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.1 mM	20.85 mL	104.25 mL	208.5 mL
0.5 mM	4.17 mL	20.85 mL	41.7 mL
1 mM	2.09 mL	10.43 mL	20.85 mL
5 mM	0.42 mL	2.09 mL	4.17 mL

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产品说明书 for Cytochalasin B

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Cytochalasin B

参考文献是支持产品生物活性的出版物。

Theodoropoulos et al (1994) Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping. Biochem.Pharmacol. 47 1875 PMID: 8204105

Whitesell et al (2005) Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line. Biochem.J. 386 245 PMID: 15473866

Buldak et al (2014) Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment. Eur.J.Histochem. 58 2408 PMID: 25308845

If you know of a relevant reference for Cytochalasin B, please let us know.

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