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Submit ReviewCannabinoid receptor agonist (Ki values are 5.05 and 3.13 nM for CB1 and CB2 receptors respectively; EC50 values are 6, 0.4 and 8 nM at CB1, CB2 and GPR55 receptors respectively). Major psychoactive constituent of marijuana. Shown to inhibit lung cancer growth and metastasis in an in vivo mouse model.
分子量 | 314.46 |
公式 | C21H30O2 |
储存 | Store at RT |
纯度 | ≥95% (HPLC) |
CAS Number | 1972-08-3 |
Smiles | CCCCCC1=CC3=C([C@]2([H])C=C(C)CC[C@]([H])2C(C)(C)O3)C(O)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Ryberg et al (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 152 1092 PMID: 17876302
Pertwee (2008) The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br.J.Pharmacol. 153 199 PMID: 17828291
Preet et al (2008) Δ9-tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene 27 339 PMID: 17621270
关键词: D9-Tetrahydrocannabinol, D9-Tetrahydrocannabinol supplier, cannabinoids, receptor, agonists, psychoactive, Non-Selective, Receptors, Δ9-Tetrahydrocannabinol, Delta9-Tetrahydrocannabinol, cb2r, cb1r, THC, Non-selective, Cannabinoids, 2741, Tocris Bioscience
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