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说明： Endogenous CB1 agonist
别名： Docosatetraenylethanolamide
化学名： N-(2-Hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenamide
生物活性 for DEA
DEA is a potent endocannabinoid and anandamide (Cat. No. 1339) analog that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (Ki = 34.4 nM). Cannabimimetic in vivo.
技术数据 for DEA
| 分子量 | 375.59 |
| 公式 | C24H41NO2 |
| 储存 | Desiccate at -20°C |
| CAS Number | 150314-35-5 |
| PubChem ID | 5282273 |
| InChI Key | FMVHVRYFQIXOAF-DOFZRALJSA-N |
| Smiles | CCCCC\C=C/C\C=C/C/C=C\C/C=C\CCCCCC(NCCO)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for DEA
参考文献 for DEA
参考文献是支持产品生物活性的出版物。
Barg et al (1995) Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. Eur.J.Pharmacol. 287 145 PMID: 8749028
Hanus et al (1993) Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J.Med.Chem. 36 3032 PMID: 8411021
Walter et al (2001) Microglial cells produce endocannabinoids and express functional cannabinoid receptors: evidence that docosatetraenylethanolamide (DEA) is an additional endocannabinoid. Soc.Neurosci.Abstr. 634.16
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关键词: DEA, DEA supplier, Endogenous, CB1, agonists, Cannabinoids, Receptors, cb1r, Docosatetraenylethanolamide, 1485, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.
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