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DH 97

Cat. No. 1218 2 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： MT2 receptor antagonist
化学名： N-Pentanoyl-2-benzyltryptamine
说明书
引用文献 (2)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for DH 97

DH 97 is a relatively potent MT2 melatonin receptor antagonist (pKi value = 8.03), displaying 89- and 229-fold selectivity over MT1 and GPR50 (melatonin-related orphan receptor) respectively.

技术数据 for DH 97

分子量 334.46
公式 C22H26N2O
储存 Store at RT
CAS Number 220339-00-4
PubChem ID 3467177
InChI Key HDOIPCLEKCEANF-UHFFFAOYSA-N
Smiles CCCCC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for DH 97

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 100

制备储备液 for DH 97

以下数据基于产品分子量 334.46。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL
10 mM 0.3 mL 1.49 mL 2.99 mL
50 mM 0.06 mL 0.3 mL 0.6 mL

Molarity Calculator

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Dilution Calculator

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参考文献 for DH 97

参考文献是支持产品生物活性的出版物。

Teh and Sugden (1998) Comparison of the relationships of melatonin receptor agonists and antagonists; lengthening the N-acyl side chain has differing effects on potency on Xenopus melanophores. Naunyn Schmiedebergs Arch.Pharmacol. 358 522 PMID: 9840420

Ting et al (1999) Molecular and pharmacological evidence for MT1 melatonin receptor subtype in the tail artery of juvenile Wistar rats. Br.J.Pharmacol. 127 987 PMID: 10433507

If you know of a relevant reference for DH 97, please let us know.

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关键词: DH 97, DH 97 supplier, MT2, receptor, antagonist, Receptors, Melatonin, DH97, (MT), 1218, Tocris Bioscience

2 篇 DH 97 的引用文献

引用文献是使用了 Tocris 产品的出版物。 DH 97 的部分引用包括：

Kojima et al (2011) Melatonin inhibits tachykinin NK2 receptor-triggered 5-HT release from guinea pig isolated colonic mucosa. Br J Pharmacol 162 1179 PMID: 21091649

Sjöblom et al (2003) Melatonin-induced calcium signaling in clusters of human and rat duodenal enterocytes. BMC Neurosci 284 G1034 PMID: 12584110

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