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DJ-V 159

Cat. No. 6645 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6645 has been discontinued.

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说明： GPRC6A agonist
化学名： N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for DJ-V 159

DJ-V 159 is a GPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.

技术数据 for DJ-V 159

分子量 502.37
公式 C24H12F6N4O2
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 2253744-53-3
PubChem ID 137319717
InChI Key VEVNLJLJLVESLL-UHFFFAOYSA-N
Smiles O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C2=CC(C(NC3=CC(C(F)(F)F)=C(C#N)C=C3)=O)=CC=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for DJ-V 159

参考文献是支持产品生物活性的出版物。

Pi et al (2018) Computationally identified novel agonists for GPRC6A. PLoS One 13 e0195980 PMID: 29684031

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关键词: DJ-V 159, DJ-V 159 supplier, DJ-V159, CPRC6A, agonists, agonism, diabetes, insulin, β, beta, cells, Orphan, 7-TM, Receptors, 6645, Tocris Bioscience

1 篇 DJ-V 159 的引用文献

引用文献是使用了 Tocris 产品的出版物。 DJ-V 159 的部分引用包括：

Sheng et al (2023) Substance P aggravates ligature-induced periodontitis in mice. Front Immunol 14 1099017 PMID: 37122730

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