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Submit ReviewHigh affinity antagonist at the ion channel on the NMDA receptor.
分子量 | 381.47 |
公式 | C19H23N.C4H4O4 |
储存 | Store at RT |
CAS Number | 207461-99-2 |
PubChem ID | 16657069 |
InChI Key | AEHZEDLXDLPQQD-BTJKTKAUSA-N |
Smiles | OC(=O)\C=C/C(O)=O.C(C(N1CCCCC1)C1=CC=CC=C1)C1=CC=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Ragawski (1993) Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines. TiPS 14 325 PMID: 7504360
关键词: (±)-1-(1,2-Diphenylethyl)piperidine maleate, (±)-1-(1,2-Diphenylethyl)piperidine maleate supplier, NMDA, antagonists, ion, channel, site, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0360, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 (±)-1-(1,2-Diphenylethyl)piperidine maleate 的部分引用包括:
Ataka et al (2012) Alteration of antral and proximal colonic motility induced by chronic psychological stress involves central urocortin 3 and vasopressin in rats. Am J Physiol Gastrointest Liver Physiol 303 G519 PMID: 22651925
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.