(±)-AC 7954 hydrochloride

Name: (±)-AC 7954 hydrochloride
Brand: Tocris Bioscience
SKU: 2484

Cat. No. 2484 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2484 has been discontinued.

View all Urotensin-II Receptors products.

说明： Non-peptide UT receptor agonist

化学名： (±)-3-(4-Chlorophenyl)-3-[2-(dimethylamino)ethyl]-3,4-dihydro-1H-2-benzopyran-1-one hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for (±)-AC 7954 hydrochloride

(±)-AC 7954 hydrochloride is a highly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC₅₀ values are 6.5 and 6.7 respectively).

技术数据 for (±)-AC 7954 hydrochloride

分子量	366.28
公式	C₁₉H₂₀ClNO₂.HCl
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	477313-09-0
PubChem ID	9907171
InChI Key	AJPGLOWFIBOGMH-UHFFFAOYSA-N
Smiles	Cl.CN(C)CCC1(CC2=CC=CC=C2C(=O)O1)C1=CC=C(Cl)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for (±)-AC 7954 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for (±)-AC 7954 hydrochloride

参考文献是支持产品生物活性的出版物。

Croston et al (2002) Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954). J.Med.Chem. 45 4950 PMID: 12408704

Lavecchia et al (2005) Architecture of the human urotensin II receptor: comparison of the binding domains of peptide and non-peptide urotensin II agonists. J.Med.Chem. 48 2480 PMID: 15801838

Lehmann et al (2006) Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J.Med.Chem. 49 2232 PMID: 16570919

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关键词: (±)-AC 7954 hydrochloride, (±)-AC 7954 hydrochloride supplier, Non-peptide, UT, receptor, agonists, Receptors, Urotensin-II, (±)-AC7954, hydrochloride, 2484, Tocris Bioscience

篇 (±)-AC 7954 hydrochloride 的引用文献

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目前没有 (±)-AC 7954 hydrochloride 的引用文献。