(±)-Cloprostenol sodium salt

Name: (±)-Cloprostenol sodium salt
Brand: Tocris Bioscience
SKU: 2295

Cat. No. 2295 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2295 has been discontinued.

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说明： Water-soluble PGF₂_α analog and potent FP receptor agonist

化学名： (5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid monosodium salt

纯度： ≥98% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for (±)-Cloprostenol sodium salt

(±)-Cloprostenol sodium salt is a water-soluble prostaglandin F_2α (PGF_2α) analog; acts as a potent FP receptor agonist (EC₅₀ = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo.

技术数据 for (±)-Cloprostenol sodium salt

分子量	446.9
公式	C₂₂H₂₈ClNaO₆
储存	Desiccate at -20°C
纯度	≥98% (HPLC)
CAS Number	55028-72-3
PubChem ID	17756794
InChI Key	IFEJLMHZNQJGQU-KXXGZHCCSA-M
Smiles	[Na+].O[C@@H](COC1=CC(Cl)=CC=C1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for (±)-Cloprostenol sodium salt

分析证书/产品说明书

化学品安全技术说明书

参考文献 for (±)-Cloprostenol sodium salt

参考文献是支持产品生物活性的出版物。

Dukes et al (1974) Potent luteolytic agents related to prostaglandin F_2α. Nature 250 330 PMID: 4853720

Griffin et al (1998) Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J.Pharmacol.Exp.Ther. 286 411 PMID: 9655886

Serrero and Lepak (2002) Prostaglandin F_2α receptor (FP receptor) agonists are potent adipose differentiation inhibitors for primary culture of adipocyte precursors in defined medium. Biochem.Biophys.Res.Comm. 233 200

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关键词: (±)-Cloprostenol sodium salt, (±)-Cloprostenol sodium salt supplier, Water-soluble, PGF2alpha, potent, FP, receptor, agonists, Receptors, Prostaglandin, Prostanoid, 2295, Tocris Bioscience

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