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Submit Review(±)-MDMA hydrochloride
说明： Inhibitor of 5-HT and dopamine uptake; hallucinogenic
别名： Methylenedioxymethamphetamine hydrochloride
化学名： ±-N,α,-Dimethyl-3,4-methylenedioxyphenethylamine hydrochloride
纯度： ≥98% (HPLC)
生物活性 for (±)-MDMA hydrochloride
(±)-MDMA hydrochloride is a hallucinogenic compound that inhibits 5-HT and dopamine uptake.
技术数据 for (±)-MDMA hydrochloride
| 分子量 | 229.7 |
| 公式 | C11H15NO2.HCl |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 64057-70-1 |
| PubChem ID | 71285 |
| InChI Key | LUWHVONVCYWRMZ-UHFFFAOYSA-N |
| Smiles | CC(NC)CC1=CC(OCO2)=C2C=C1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (±)-MDMA hydrochloride
参考文献 for (±)-MDMA hydrochloride
参考文献是支持产品生物活性的出版物。
Iravani et al (2000) Direct effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin or DA release and uptake in the caudate putamen, nucleus accumbens, substantia nigra pars reticulata, and the dorsal raphe nucleus slices. Synapse 36 275 PMID: 10819905
Fleckenstein et al (2007) New insights into the mechanism of action of amphetamines. Annu.Rev.Pharmacol.Toxicol. 47 681 PMID: 17209801
Boyle et al (2007) MDMA ("ecstasy") suppresses the innate IFN-γ response in vivo: a critical role for the anti-inflammatory cytokine IL-10. Eur.J.Pharmacol. 572 228 PMID: 17689526
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关键词: (±)-MDMA hydrochloride, (±)-MDMA hydrochloride supplier, inhibitors, inhibits, 5-HT, dopamine, reuptake, hallucinogenic, Serotonin, Transporters, SERT, 5-Hydroxytryptamine, Monoamine, Neurotransmitter, DAT, Methylenedioxymethamphetamine, hydrochloride, 92279-84-0, (±)-Methylenedioxymethamphetamine, Dopamine, 3027, Tocris Bioscience
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Reinstatement of MDMA seeking by exposure to discrete drug-conditioned cues.
By
Kevin Ball on 01/25/2019
分析类型： In Vivo
种属： Rat
Rats self-administered MDMA (0.30 mg/kg/infusion, i.v.). We then showed that, following extinction of MDMA seeking, discrete MDMA-associated cues reinstated MDMA-seeking behavior. Also, the magnitude of reinstatement was positively correlated with the level of responding during MDMA self-administration.
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.