Dobutamine hydrochloride

Cat. No. 0515 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： α₁, β₁ and β₂ agonist

化学名： 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride

纯度： ≥98% (HPLC)

引用文献 (3)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Dobutamine hydrochloride

Dobutamine hydrochloride is a β₁- and β₂-adrenoceptor agonist with some action at the α₁-adrenoceptor.

化合物库 for Dobutamine hydrochloride

Dobutamine hydrochloride is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。

技术数据 for Dobutamine hydrochloride

分子量	337.85
公式	C₁₈H₂₃NO₃.HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	49745-95-1
PubChem ID	65324
InChI Key	BQKADKWNRWCIJL-UHFFFAOYSA-N
Smiles	Cl.CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Dobutamine hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	33.78	100

制备储备液 for Dobutamine hydrochloride

以下数据基于产品分子量 337.85。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.96 mL	14.8 mL	29.6 mL
5 mM	0.59 mL	2.96 mL	5.92 mL
10 mM	0.3 mL	1.48 mL	2.96 mL
50 mM	0.06 mL	0.3 mL	0.59 mL

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产品说明书 for Dobutamine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Dobutamine hydrochloride

参考文献是支持产品生物活性的出版物。

Brown et al (1987) Dobutamine: positive inotropy by nonselective adrenoceptor agonism in isolated guinea pig and human myocardium. Naunyn Schmiedebergs Arch.Pharmacol. 335 385 PMID: 3600817

Deighton et al (1992) Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, DA, dobutamine, denopamine and xamoterol in isolated human right atrium. J.Pharmacol.Exp.Ther. 262 532 PMID: 1354251

Merck Index 12 3456

If you know of a relevant reference for Dobutamine hydrochloride, please let us know.

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3 篇 Dobutamine hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Dobutamine hydrochloride 的部分引用包括：

Li et al (2017) Pericytes impair capillary blood flow and motor function after chronic spinal cord injury. Nat Med 23 733 PMID: 28459438

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Biol Reprod 329 350 PMID: 19144685

Skeberdis et al (1997) Pharmacological characterization of the receptors involved in the beta-adrenoceptor-mediated stimulation of the L-type Ca²⁺ current in frog ventricular myocytes. Br J Pharmacol 121 1277 PMID: 9257904

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