Dynamin inhibitory peptide, myristoylated (control)

Name: Dynamin inhibitory peptide, myristoylated (control)
Brand: Tocris Bioscience
SKU: 1776

Cat. No. 1776 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1776 has been discontinued.

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说明： Control peptide version of dynamin inhibitory peptide, myristoylated (Cat. No. 1775)

说明书

引用文献 (3)

生物活性技术数据说明书参考文献

生物活性

Dynamin inhibitory peptide, myristoylated (control) is a control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant effect on GABA_A receptor-mediated miniature IPSPs.

Active Analog also available.

技术数据

分子量	1330.64
公式	C₆₁H₁₀₇N₁₉O₁₄
序列	QPPASNPRVR (Modifications: Gln-1 = Myr-Gln, Arg-10 = C-terminal amide)
储存	Desiccate at -20°C
PubChem ID	90488709
InChI Key	LRWOEJTUKITZIW-ZUSDHBTASA-N
Smiles	[H]N([C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(=O)CCCCCCCCCCCCC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书

分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419 PMID: 9148966

Kittler et al (2000) Constitutive endocytosis of GABA_A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972 PMID: 11050117

Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302 PMID: 12646920

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关键词: Dynamin inhibitory peptide, myristoylated (control), Dynamin inhibitory peptide, myristoylated (control) supplier, 1775, Mitosis, Dynamin, Epac, GTPases, 1776, Tocris Bioscience

3 篇 Dynamin inhibitory peptide, myristoylated (control) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Dynamin inhibitory peptide, myristoylated (control) 的部分引用包括：

Falgairolle and O'Donovan (2015) Pharmacological Investigation of Fluoro-Gold Entry into Spinal Neurons. J Neuroinflammation 10 e0131430 PMID: 26102354

Westmark et al (2010) Pin1 and PKMzeta sequentially control dendritic protein synthesis. Sci Signal 3 ra18 PMID: 20215645

Wang et al (2017) The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABAA Receptor Endocytosis in the vmPFC. J Neurosci 37 7096 PMID: 28630256