EC 23

Cat. No. 4011 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Synthetic retinoid; induces differentiation of stem cells

化学名： 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid

纯度： ≥99% (HPLC)

引用文献 (2)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for EC 23

EC 23 is a photostable synthetic retinoid; analog of ATRA (Cat. No. 0695). Displays similar activity to ATRA when tested on the embryonal carcinoma stem cell model TERA2.cl.SP12. Potently induces neural differentiation in human pluripotent embryonic stem cells.

许可信息

Sold under license from Reinnervate Limited, patent pending

化合物库 for EC 23

EC 23 is also offered as part of the Tocriscreen Stem Cell Library. 了解 Tocris 化合物库的更多信息。

技术数据 for EC 23

分子量	332.44
公式	C₂₃H₂₄O₂
储存	Store at +4°C
纯度	≥99% (HPLC)
CAS Number	104561-41-3
PubChem ID	10314719
InChI Key	OQVLOWLEEHYBJH-UHFFFAOYSA-N
Smiles	CC1(C)C2=C(C=CC(C#CC3=CC=C(C(O)=O)C=C3)=C2)C(C)(C)CC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for EC 23

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	33.24	100
	ethanol	1.66	5

制备储备液 for EC 23

以下数据基于产品分子量 332.44。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.01 mL	15.04 mL	30.08 mL
5 mM	0.6 mL	3.01 mL	6.02 mL
10 mM	0.3 mL	1.5 mL	3.01 mL
50 mM	0.06 mL	0.3 mL	0.6 mL

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产品说明书 for EC 23

分析证书/产品说明书

化学品安全技术说明书

参考文献 for EC 23

参考文献是支持产品生物活性的出版物。

Christie et al (2008) Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org.Biomol.Chem. 6 3497 PMID: 19082150

Barnard et al (2009) Synthetic retinoids: structure-activity relationships. Chemistry 15 11430 PMID: 19821467

Maltman et al (2009) Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol.Biosyst. 5 458 PMID: 19381361

If you know of a relevant reference for EC 23, please let us know.

按标靶查看相关产品

关键词: EC 23, EC 23 supplier, retinoids, synthetic, stem, cells, induces, differentiation, ATRA, retinoic, acid, receptors, agonists, EC23, Retinoic, Acid, Receptors, Retinal, Stem, Cells, ESCs, and, iPSC, 4011, Tocris Bioscience

2 篇 EC 23 的引用文献

引用文献是使用了 Tocris 产品的出版物。 EC 23 的部分引用包括：

Santos-Ferreira et al (2019) Morpho-Rheological Fingerprinting of Rod Photoreceptors Using Real-Time Deformability Cytometry. Cytometry A PMID: 31107590

Ying et al (2020) Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production via Multiple Mechanisms in Differentiated Airway Epithelial Cells. Front Cell Infect Microbiol 10 278 PMID: 32637364

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Retinoid Receptors Scientific Review

Written by Alexander Moise, this review summarizes the nature of retinoid receptors, their isotype and isoform variants and modulation of retinoid signaling. Compounds available from Tocris are listed.