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Epoprostenol

Cat. No. 2989 2 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Endogenous IP receptor agonist
别名： Prostaglandin I2,Prostacyclin
化学名： (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
纯度： ≥99% (HPLC)
说明书
引用文献 (2)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Epoprostenol

Epoprostenol is an endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.

技术数据 for Epoprostenol

分子量 374.45
公式 C20H31NaO5
储存 Store at -80°C
纯度 ≥99% (HPLC)
CAS Number 61849-14-7
PubChem ID 6364626
InChI Key LMHIPJMTZHDKEW-XQYLJSSYSA-M
Smiles [Na+].CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2O\C(C[C@H]12)=C/CCCC([O-])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Epoprostenol

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 37.44 100

制备储备液 for Epoprostenol

以下数据基于产品分子量 374.45。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.67 mL 13.35 mL 26.71 mL
5 mM 0.53 mL 2.67 mL 5.34 mL
10 mM 0.27 mL 1.34 mL 2.67 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

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产品说明书 for Epoprostenol

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Epoprostenol

参考文献是支持产品生物活性的出版物。

Kobzar et al (2001) Comparison of anti-aggregatory effects of PGI2, PGI3 and ilo. on human and rabbit platelets. Cell.Physiol.Biochem. 11 279 PMID: 11684817

Oliva and Nicosia (1987) PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art. Pharmacol.Res.Comm. 19 735

If you know of a relevant reference for Epoprostenol, please let us know.

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关键词: Epoprostenol, Epoprostenol supplier, Endogenous, IP, receptors, agonists, Prostanoid, prostaglandins, prostacyclins, eicosanoids, Prostaglandin, I2, Prostacyclin, Receptors, 2989, Tocris Bioscience

2 篇 Epoprostenol 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Epoprostenol 的部分引用包括：

Armstrong et al (2015) Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction. Blood 126 e11 PMID: 26215112

Barwari et al (2018) Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight 3 PMID: 30385722

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