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ESI 05

Cat. No. 6320 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Epac2 inhibitor
化学名： 1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for ESI 05

ESI 05 is an EPAC2 inhibitor. Inhibits cAMP binding to EPAC2 and cAMP mediated EPAC2 guanine nucleotide exchange factor (GEF) activity (IC50 = 0.4 μM).

化合物库 for ESI 05

ESI 05 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for ESI 05

分子量 274.38
公式 C16H18O2S
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 5184-64-5
PubChem ID 272513
InChI Key CGPHOZWFSFNOEQ-UHFFFAOYSA-N
Smiles CC1=CC=C(S(=O)(C2=C(C=C(C=C2C)C)C)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for ESI 05

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 27.44 100
ethanol 27.44 100

制备储备液 for ESI 05

以下数据基于产品分子量 274.38。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.64 mL 18.22 mL 36.45 mL
5 mM 0.73 mL 3.64 mL 7.29 mL
10 mM 0.36 mL 1.82 mL 3.64 mL
50 mM 0.07 mL 0.36 mL 0.73 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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参考文献 for ESI 05

参考文献是支持产品生物活性的出版物。

Tsalkova et al (2012) Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proc.Natl.Acad.Sci.USA. 109 18613 PMID: 23091014

If you know of a relevant reference for ESI 05, please let us know.

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关键词: ESI 05, ESI 05 supplier, ESI05, EPAC2, inhibitors, inhibits, EPAC, epac, exchange, proteins, directly, activated, by, cAMP, Rap, guanine, nucleotide, factor, 4, RAPGEF4, 6320, Tocris Bioscience

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