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Submit ReviewFK 409
Discontinued Product
This product has been withdrawn from sale and is superseded by DETA NONOate (Cat. No. 6077)
说明： NO donor
别名： NOR-3,(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
化学名： (2E,3E)-4-Ethyl-2-(hydroxyimino)-5-nitro-3-hexenamide
纯度： ≥98% (HPLC)
生物活性 for FK 409
NO donor; exhibits vasorelaxant (EC50 = 3.9 nM) and antiplatelet activities (IC50 = 4.9 μM). Cell permeable.
技术数据 for FK 409
| 分子量 | 215.21 |
| 公式 | C8H13N3O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 138472-01-2 |
| PubChem ID | 6437875 |
| InChI Key | MZAGXDHQGXUDDX-AGLLBGTNSA-N |
| Smiles | CC(/C(CC)=C/C(C(N)=O)=N\O)[N+]([O-])=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for FK 409
参考文献 for FK 409
参考文献是支持产品生物活性的出版物。
Fukuyama et al (1997) Structure-activity relationships of spontaneous nitric oxide releasers, FK409 and its derivatives. J.Pharmacol.Exp.Ther. 282 236 PMID: 9223559
关键词: FK 409, FK 409 supplier, FK409, NO, donors, nitric, oxide, vasorelaxant, cell, permeable, NOR-3, (±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide, Donors, /, Precursors, ROS, 3105, Tocris Bioscience
1 篇 FK 409 的引用文献
引用文献是使用了 Tocris 产品的出版物。 FK 409 的部分引用包括：
Cortés-Montero et al (2019) The axonal motor neuropathy-related HINT1 protein is a zinc- and calmodulin-regulated cysteine SUMO protease. Antioxid Redox Signal PMID: 31088288
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