Foxy 5

Cat. No. 5461 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Wnt5a peptide mimetic

纯度： ≥95% (HPLC)

引用文献 (1)

通路 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Foxy 5

Foxy 5 is a Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.

技术数据 for Foxy 5

分子量	694.77
公式	C₂₆H₄₂N₆O₁₂S₂
序列	MDGCEL (Modifications: Met-1 = N-Formyl)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	881188-51-8
PubChem ID	44628955
InChI Key	WFZPJYYCTSHDJI-ATIWLJMLSA-N
Smiles	[H]N([C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(O)=O)C(=O)[C@H](CCSC)NC=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Foxy 5

溶解性	Soluble to 1 mg/ml in PBS (pH 7.4)

产品说明书 for Foxy 5

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Foxy 5

参考文献是支持产品生物活性的出版物。

Säfholm et al (2008) The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin.Cancer Res. 14 6556 PMID: 18927296

Säfholm et al (2006) A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J.Biol.Chem. 281 2740 PMID: 16330545

If you know of a relevant reference for Foxy 5, please let us know.

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关键词: Foxy 5, Foxy 5 supplier, Foxy5, wnt5a, peptide, mimetic, Other, Wnt, Signaling, 5461, Tocris Bioscience

1 篇 Foxy 5 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Foxy 5 的部分引用包括：

Ling et al (2021) Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids. Cell Stem Cell 28 1090-1104.e6 PMID: 33915081

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Pathways for Foxy 5

Wnt Signaling Pathway

The Wnt pathway is involved in cellular differentiation and proliferation in adult tissues and also during embryogenesis. Disturbances within the pathway may lead to the formation of tumors and promote metastasis.